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USP Amlodipine, Valsartan, and Hydrochlorothiazide Tablets –Assay and Impurities- Amlodipine,Valsartan,Hydrochlorothiazide Standard solution Chromatogram USP-Impurities

Application Detail (App ID: 28202)

Part No:00F-4784-E0
Dimensions:150 x 4.6 mm ID
Elution Type:Gradient
Elution A:0.1% Orthophosphoric acid in water. (1 ml of Orthophosphoric acid in dissolved in 1000 ml of water. Filtered through 0.22µ Nylon filter. Mobile phase A: Acetonitrile: water and Phosphoric acid in ratio of 50:950:1 ml v/v/v.
Elution B:0.1% Orthophosphoric acid in water. (1 ml of Orthophosphoric acid in dissolved in 1000 ml of water. Filtered through 0.22µ Nylon filter. Mobile phase B: Acetonitrile: water and Phosphoric acid in ratio of 950:50:1 ml v/v/v.
Gradient Profile:
Step No. Time (min) Pct A Pct B
1 0 95 5
2 3 50 50
3 6 40 60
4 10 5 95
5 10.1 95 5
6 15 95 5

Flow Rate:1.5 mL/min
Col. Temp: 40 °C
Detection: LC/UV (DAD, PDA) @ 210.0000000000 (0°C)

Analyte Details

Analyte Detail not available

1
Benzothiadiazine related Com-A
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2
Hydrochlorothiazide
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3
Amlodipine related compound A
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4
Amlodipine
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5
Valsartan
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