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SecurityGuard™

  • Extends HPLC Column Lifetime
  • Virtually No Change in Chromatography
  • Universal Column Compatibility
  • Simple to Use
  • SecurityGuard is a universal HPLC guard cartridge system designed to effectively (and inexpensively), protect all your valuable analytical and prep HPLC columns from the damaging effects of chemical contaminants, without altering your chromatographic results.

    Change the Guard Cartridge
    NOT Your HPLC Column

    Watch our SecurityGuard Videos

    SecurityGuard is patented by Phenomenex. U.S. Patent No. 6,162,632




Technical Documents:

Document Type:
Document Type Title
Technical Notes 15 Sugars Analyzed by LC-RI using Luna Omega SUGAR LC Columns

Summary

Sugars are critical components/ingredients in many food and beverage products. Monitoring their presence and quantity is crucial for both label claim verification as well as quality in manufacturing. Developed below is a method for 15 sugars with great separation between various monosaccharides, disaccharides, and oligosaccharides.

Other Cannabis Testing Guide 2022 (LC/GC/SP)

Summary

The latest applications and resources for testing potency, pesticides, mycotoxins, terpenes, and residual solvents. Techniques: HPLC, UHPLC, and GC.

Other Chemical Industry LC & GC Separation Solutions Guide

Summary

At our core, Phenomenex is a separation science company that creates unique technologies to provide solutions for our customers. In this guide you will find key separation solutions for the Chemical industry, powered by Phenomenex separation products.

Technical Notes Chiral Separation of Lorazepam using a Lux 5 μm i-Amylose-1 Column

Summary

A simple and robust method was developed for the separation between each Lorazepam enantiomer using a Lux i-Amylose-1 chiral column.

Technical Notes Chiral Separation of Naproxen by High Performance Liquid Chromatography on Lux i-Amylose-1

Summary

In this technical note, we report the chiral separation of racemic Naproxen using the immobilized polysaccharide-based chiral stationary phase Lux i-Amylose-1. Under optimal conditions, the racemic Naproxen was efficiently separated with a resolution factor of 2.33 and a separation factor (alpha) of 1.16. This method can be used for the enantiomeric separation and purity assessment of S-Naproxen, the Active Pharmaceutical Ingredient (API).

Other Drugs and Metabolites Guide

Summary

Effective separation of closely related analytes of interest can be a difficult task to achieve. This guides provides helpful strategies for effective HPLC/UHPLC column selection.

Other Environmental Applications Guide

Summary

Access the latest LC-MS/MS applications for environmental testing including: - Pesticides / Herbicides - Perfluoroalkyl Substances (PFAS) - PPCP's and Hormones - Marine Toxins - Environmental Contaminants

Brochures Extend your Analytical and Preparative HPLC/ SFC Column Lifetimes

Summary

See how easy it is to extend your analytical and preparative HPLC/ SFC column lifetimes

Technical Notes Extended Gemini C18 Column Lifetime Using SecurityGuard

Summary

Extended Gemini C18 Column Lifetime Using SecurityGuard

Technical Notes Extended Gemini NX-C18 Column Lifetime Using SecurityGuard

Summary

Extended Gemini NX-C18 Column Lifetime Using SecurityGuard

Technical Notes Extended Luna C18(2) Column Lifetime Using SecurityGuard

Summary

Extended Luna C18(2) Column Lifetime Using SecurityGuard

Supporting Docs Frequently Asked Questions for UHPLC/HPLC

Summary

Frequently Asked Questions for UHPLC/HPLC

Other HPLC/UHPLC Column Phase Selection Chart

Summary

Specifically designed for successful and reproducible method development and transfer. Comparison of achiral stationary phases based on material characteristics and the hydrophobic subtraction model.

Technical Notes Ion-Exchange Chromatography for Charge Variant Analysis of Trastuzumab under pH and Salt Gradients using a bioZen 6 μm WCX Column

Summary

Excellent separation of acidic and basic variants from the neutral trastuzumab with the use of the bioZen WCX ion-exchange column under both pH and salt gradients.

Brochures Kinetex and Luna Omega : Combined Performance and Selectivity Gains for HPLC/UHPLC

Summary

Kinetex Core-Shell Technology and Luna Omega Thermally Modified Particle Technology are the perfect combination to upgrade and boost performance for UHPLC, HPLC, and Preparative HPLC methods.

Brochures Kinetex Product Guide - Rock Your LC Laboratory

Summary

Kinetex Core-Shell Technology: • Obtain higher throughput without sacrificing resolution • Easy method transfer across LC system platforms • Reduce solvent consumption with faster analysis • Reach lower levels of detection and quantitation

Brochures Luna Omega SUGAR Product and Application Guide

Summary

The new Luna Omega SUGAR breaks ground as it combines the performance benefits of thermally modified fully porous particles with a novel HILIC stationary phase that excels at polar compound retention and selectivity. Improved carbohydrate retention and separation with novel HILIC selectivity. Enhanced lifetime with highly robust and efficient thermally modified fully porous particle. QC tested for sugars to ensure reliable quality.

Brochures Lux AMP Product Guide

Summary

Rapid and accurate chiral separation of amphetamine and substituted amphetamine enantiomers

Brochures Lux i-Amylose-3 Application Guide

Summary

New Lux i-Amylose-3 provides broad enantioselectivity, excellent reproducibility, and robustness even under strong organic solvents. This chiral screening application notebook covers reversed phase, normal phase, polar organic and polar ionic examples.

Brochures Lux Immobilized i-Amylose-1 Product Guide

Summary

Incredibly robust immobilized chiral columns with brilliant separation power. Lux i-Amylose-1 and i-Cellulose-5 contain a chemical crosslinking between the polysaccharide and silica supports which in turn provides incredible strong solvent (THF, DCM, DMSO, MtBE, Ethyl Acetate, etc.) robustness compared to coated phases and prevents the phase from being dissolved in strong solvents.

Brochures PFAS Analytical Workflow Solutions

Summary

Complete portfolio of solutions for PFAS Analysis

Other Pharmaceutical Analysis Guide- Formulations

Summary

Improve your formulations assays today by achieving resolution, ruggedness, and reproducibility.

Brochures Phenova PFAS CRM

Summary

PFAS CRM Native Standards for EPA methods 533 and 537.1 with full list of analytes per mix offered plus a complete list of Phenomenex PFAS products and resources for PFAS analysis.

Technical Notes Screening Approach for the Separation of Pharmaceutical Compounds using Lux Polysaccharide-Based Chiral Stationary Phases in SFC Mode (TN-9004)

Summary

In this technical note, we present various SFC screening approaches for the chiral separation of a 56-pharmaceutical compound test set using Lux polysaccharide-based chiral stationary phases. The new Lux Amylose-1 provides the largest number of baseline separations. Additional generic chiral separation strategies for SFC are highlighted for increasing success rates.

Brochures Security Family Brochure

Summary

Small things can have a huge impact on the quality of your chromatographic results. The Security Family of products was developed to allow you to protect the things that matter most: workplace safety, columns, results, and time efficiency.

Brochures SecurityGuard Column Protection Family Brochure (UHPLC, HPLC, PREP, SFC)

Summary

Get complete protection for your UHPLC, HPLC, SFC and Preparative columns with Securityguard universal guard cartridge system

Technical Notes Simple Sugars Analysis from Fruit Berries by LC-ELSD using Luna Omega SUGAR LC Columns

Summary

Berry fruits including Goji berry and Zante currant have increased in popularity due to their rich content of macronutrients, other phytochemicals, as well as sugars. Sugars have a major effect on the flavor of these berries as well as nutritional acceptance. Developed below, using the Luna Omega 3 μm SUGAR LC column is the separation of simple sugars from Goji berries and Zante currants. Excellent separation of glucose and fructose is provided leading to accurate quantitation for effective monitoring of sugar content as well as flavor profiles.

Technical Notes Simple Sugars Analysis from Soft Drinks using Luna Omega SUGAR LC Columns

Summary

Simple sugars are the smallest and simplest carbohydrates found in many food products, especially soft drinks. Sugar analysis is critical to food quality as well as labeling requirements for nutritional content. Developed below, using the Luna Omega 3 μm SUGAR LC column, is the separation of simple sugars from various cola products, producing excellent separation of glucose and fructose

Technical Notes Simple Sugars Analysis from Wine by LC-RI using Luna Omega SUGAR LC Columns

Summary

Sugar analysis, especially for glucose and fructose, is an effective and important step for wine makers to manage the fermentation process in wine production. Full resolution between fructose and glucose can ensure accurate results. Developed below, using the Luna Omega 3 μm SUGAR LC column, is the separation of simple sugars from red, white and dessert wine, producing excellent separation of glucose and fructose leading to more accurate quantitation for effective fermentation monitoring.

Technical Notes Sugar Analysis from Animal Feed using Luna Omega SUGAR LC Columns

Summary

Evaluating the sugar content of animal feed is important for providing proper nutrition and strong animal performance. Using the Luna Omega SUGAR column, the six sugars were fully resolved with better than baseline resolution. The gradient method also resolved an interference peak near fructose on the horse feed sample.

Technical Notes Sugar Analysis from Milk using Luna Omega SUGAR LC Columns

Summary

Sugar content testing is a commonly performed analysis in food laboratories. Determining sugar content is particularly important for milk where lactose is the main sugar present. While lactose is a significant energy source in milk, individuals who are lactose-intolerant have a lactase enzyme deficiency and cannot fully digest lactose. Using the Luna Omega SUGAR column, six sugars and one sugar alcohol were separated in ten minutes. Using the Luna Omega SUGAR column, we were able to analyze sugars in a variety of cow’s milk, lactose free milk, and infant formula.

Other The Ultimate Guide to HPLC/UHPLC Reversed Phase Selectivity

Summary

Follow this Step-by-Step Selectivity Guide this Guide is an easy overview of the reversed phase HPLC/UHPLC options available to you. At a glance, you’ll be able to quickly understand the differences between the columns available and select the right solution for your specific method and goals.

Brochures Vitamin Testing Brochure

Summary

Top applications and reproducible Phenomenex products to achieve your vitamin testing needs • Simple cleanup procedures • Rapid HPLC analysis • Accurate, reproducible results

Other Drugs and Metabolites Guide Japanese (医薬品および 代謝物の分離)

Summary

密接に関連する分析対象物の効果的な分離作業は達成が困難になる可能性があります。こちらのガイドでは、効果的なHPLC/UHPLCカラム選択に役立つ戦略を提供します。- Effective separation of closely related analytes of interest can be a difficult task to achieve. This guides provides helpful strategies for effective HPLC/UHPLC column selection.

Supporting Docs Find Your Accessory Sidekick

Summary

You can never have too many accessory sidekicks to help you save your columns, defeat evil contaminated particles, and create less system maintenance downstream. Find your ideal sidekick today!

Brochures Extend the Life of Your Valuable GPC Columns

Summary

Simple-to-use SecurityGuard GPC protects ANY non-aqueous GPC column. Extremely economical alternative to the typical GPC guard columns.

Other Find Your Lab Accessory Sidekick Poster

Summary

You can never have too many accessory sidekicks to help you save your columns, defeat evil contaminated particles, and create less system maintenance downstream. Find your ideal sidekick today!

Brochures HPLC Column and System Protection Essentials/ Accessories

Summary

HPLC Column and System Protection Essentials/ Accessories

Other Safety Data Sheet for Silica-Based HPLC Columns

Summary

Safety Data Sheet for Silica-Based HPLC Columns

Supporting Docs SecurityGuard Standard and PREP Instruction Guide

Summary

SecurityGuard Standard, ULTRA and PREP Instruction Guide

Other The Quickest Route Through Chromatography Obstacles

Summary

An accessories guide that will help you find the quickest solution to your chromatography obstacle.

Other Clinical Research Accessories Guide

Summary

Find the accessories you need to complete your clinical research assays.

Brochures Kinetex and Luna Omega : Combined Performance and Selectivity Gains for HPLC/UHPLC - Japanese

Summary

KinetexとLuna Omegaカラムを使用し、UHPLC、HPLCおよび分取HPLCメソッドのパフォーマンスが向上出来ます。

Brochures SecurityGuard HPLC/UHPLC Column Protection Brochure - Japanese

Summary

UHPLC、HPLC および分取カラムを保護 し、寿命を延ばします。

Brochures Luna Omega SUGAR Product and Application Guide- Japanese

Summary

新しいLuna Omega Sugarは、熱処理済み全多孔性充填剤の性能上の利点と、極性化合物の保持と選択性に優れた新型HILIC固定相を組み合わせた革新的なカラムです。 高い堅牢性、効果的な熱処理技術による細孔構造によりカラムの寿命を延ばすことが出来ます。 信頼される品質を保証するためのQCテストにも合格しています。 - The new Luna Omega SUGAR breaks ground as it combines the performance benefits of thermally modified fully porous particles with a novel HILIC stationary phase that excels at polar compound retention and selectivity. Improved carbohydrate retention and separation with novel HILIC selectivity. Enhanced lifetime with highly robust and efficient thermally modified fully porous particle. QC tested for sugars to ensure reliable quality.

Supporting Docs SecurityGuard GPC Column Installation Instructions

Summary

SecurityGuard GPC Column Installation Instructions

Part Number:AJ0-8617

Description:SecurityGuard SFC PREP Cartridge Holder Kit, 21.2mm ID, Ea

Technique:High Performance Liquid Chromatography (HPLC)

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