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Finish First with Monolithic HPLC Columns

Monolithic silica-based HPLC columns that are designed for high-throughput analysis and the direct injection of dirty or viscous samples.

  • Reduce run times with extremely high flow rates (up to 9 mL/min)
  • “Dilute-and-Shoot” dirty biological samples
  • Scalable from capillary to semi-prep column dimensions


Technical Specifications:

Phase

Technical Documents:

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Document Type Title
Technical Notes Direct Plasma Analysis of Drug Compounds Using Onyx Monolithic Columns (TN-1033)

Summary

In this study, we present an evaluation of using Onyx™ Monolithic columns for direct injections of serum samples spiked with a mix of 11 different pharmaceuticals. We demonstrate consistent and reproducible performance with over one hundred direct serum injections.

Brochures Onyx Brochure

Summary

Let Onyx columns improve your sample throughput

Supporting Docs Onyx Capillary Column Reference Sheet

Summary

Guidelines for using Onyx capillary columns for general analysis and method development

Supporting Docs Onyx Column Care Note

Summary

Onyx Column Care Note

Other Pharmaceutical Analysis Guide- Formulations

Summary

Improve your formulations assays today by achieving resolution, ruggedness, and reproducibility.

Supporting Docs Using Onyx in ADME/DMPK Environments

Summary

Guidelines for using Onyx in ADME/DMPK environments

Technical Notes Advantage of Silica Monolithic HPLC Columns (TN-1025)

Summary

In this note, we demonstrate the reproducibility of different batches of Onyx™ Monolithic C18 columns.

Supporting Docs Onyx 2 mm ID Reference Sheet

Summary

Explanation of the benefits of Onyx 2 mm monolithic HPLC columns

Supporting Docs Using Onyx for Proteomics/Biomarker Applications

Summary

Guidelines for using Onyx for proteomics/biomarker applications

Other USP Allowable Adjustments Guide

Summary

Quickly view the allowable adjustments that have been outlined by the United States Pharmacopeia (USP) and then select the proper Phenomenex column for your monograph using this simple guide.

Other USP Allowable Adjustments Guide Japanese (米国薬局方（USP)メソッドの許容調整)

Summary

こちらのガイドを使用し、米国薬局方（USP）によって概説されている許容可能な調整をすばやく確認し、モノグラフ（医薬品各条）に適切なPhenomenexカラムを選択出来ます。- Quickly view the allowable adjustments that have been outlined by the United States Pharmacopeia (USP) and then select the proper Phenomenex column for your monograph using this simple guide.

Other Allowable Adjustments to European Pharmacopoeia (EP) Methods

Summary

Easily determine the allowable adjustments that can be made to European Pharmacopoeia (EP) methods and find the right column for your method.

Supporting Docs Using Onyx for Food and Beverage Applications

Summary

Guidelines for using Onyx for food and beverage applications

Supporting Docs HPLC Column Care Guide

Summary

HPLC Column Care Guide

Part Number:AQ0-7654

Description:Onyx Column Coupler, PEEK, 0.020in ID Bore, Ea

Technique:High Performance Liquid Chromatography (HPLC)

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