Acids, Neutrals and Bases Using Novum Simplified Liquid Extraction (SLE) (TN-0121)

Abstract:

We developed a SLE application for acids (THC-COOH), neutrals (barbiturates), and bases (Norbuprenorphine and Buprenorphine) from a urine matrix containing β-glucuronidase followed by two LC-MS/MS methods using a Kinetex® EVO C18 LC column and SCIEX API 4000™ mass spec in negative mode electrospray ionization (ESI-) and a Kinetex Biphenyl LC column and SCIEX API 4000 mass spec in positive mode electrospray ionization (ESI+).

Document Type:

Technical Notes

Industries:

Clinical Forensics/Toxicology

Techniques:

HPLC / UHPLC Sample Prep

Brands:

Novum SLE Kinetex

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