An Optimized Protocol for the 25 mg/well Clarity OTX 96-Well Plates

Abstract:

In this application, we demonstrate that the Clarity OTX 25 mg/well format is a useful tool in the isolation, characterization, and quantitation of current antisense oligonucleotide therapeutics from mid-sized (100 μL or less) biological fluids like serum. Good linearity and sensitivity down to the single digit nanogram level were achieved when using the Clarity OTX 25 mg/well SPE plate.

Document Type:

Technical Notes

Industries:

Pharmaceutical/Biopharmaceutical

Techniques:

Oligonucleotides Sample Prep HPLC / UHPLC

Brands:

bioZen Clarity

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