Avoiding Depurination During Trityl-on Purification (TN-0008)
- Abstract:
- Trityl-on methodologies for the analysis of crude synthetic oligonucleotides has many benefits however depurination during trityl-on methodologies can lead to nucleic acid damage. This technical note explores a new trityl-on procedure that minimizes the risk of depurination.
- Document Type:
- Technical Notes
- Industries:
- Pharmaceutical/Biopharmaceutical
- Techniques:
- Sample Prep
- Brands:
- Clarity (SPE) Clarity
- PDF Link:
- Click here