Comparison of Three Unique and Complementary Micro LC Columns and Three Trap Selectivities Under Reversed Phase LC-MS/MS Conditions

Abstract:

In this application, we investigate the influence of different micro LC column and trap stationary phase selectivity combinations on chromatographic performance, sample recovery, and selectivity. We compared micro LC columns in a 50 x 0.3 mm column dimension packed with three different micro LC stationary phase chemistries: Kinetex® XB-C18, Luna® Omega PS C18, and Luna Omega Polar C18.

Document Type:

Technical Notes

Industries:

Pharmaceutical/Biopharmaceutical

Techniques:

HPLC / UHPLC

Brands:

Kinetex

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