Determination of Pesticide Residues in Cannabis by LC-MS/MS (TN-1224)

Abstract:

The current Oregon pesticides guide/ list covers a range of pesticides with diverse chemical properties. When a suitable analytical method is developed using this list, it would be easy to include additional pesticides that may be necessary in different regions. The LC-MS/MS method detailed here makes use of sample prep dilution with reversed phase HPLC column chemistries with resolving power for the multiresidue pesticides of interest. Orthoganol Kinetex® and Luna® Omega column chemistries provide a complimentary selectivity as well as sensitivity for both standards in solvent and cannabis matrix. Sensitivity is achieved on two different triple quadrupole mass spectrometer platforms: SCIEX QTRAP® 4500 and 6500+. The chromatography is demonstrated here on a SCIEX Triple Quad 3500™ on abbreviated 50 mm length columns.

Document Type:

Technical Notes

Industries:

Food & Beverage

Techniques:

HPLC / UHPLC

Brands:

Kinetex Luna

PDF Link:

Click here