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Effect of Perfluorinated Alcohols in Impurity Analysis for Synthetic Oligonucleotides


Abstract:
This applications note demonstrates the effect of changing the concentration of perfluorinated alcohols used in the impurity analysis of synthetic oligonucleotides and the improved separation using the bioZen Oligo Column of sense/anti-sense of an siRNA when decreasing HFIP concentration.
Document Type:
Technical Notes
Industries:
Pharmaceutical/Biopharmaceutical
Techniques:
Oligonucleotides
Brands:
bioZen
PDF Link:
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