Ibuprofen Tablet USP Dissolution: A Rapid HPLC Alternative to the Traditional UV Method (TN-1248)

Abstract:

In this tech note, we demonstrate an alternative approach for the dissolution test for Ibuprofen tablets which utilizes the chromatographic assay method for Ibuprofen tablets instead of the UV method outlined in the USP monograph for dissolution testing. With the use of an HPLC column for dissolution testing, the analysis time is less than 2 minutes. Column loading capacity has also been investigated in this study.

Document Type:

Technical Notes

Industries:

Pharmaceutical/Biopharmaceutical

Techniques:

HPLC / UHPLC

Brands:

Kinetex Phenex

PDF Link:

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