Mobile Phase Optimization for Aggregate Analysis of Monoclonal Antibodies (TN-1226)

Abstract:

In this technical note, two monoclonal antibodies are analyzed using sub-2 μm SEC columns using optimized mobile phase conditions. Modulation of the salt in the mobile phase showed improvements in peak shape and recovery.

Document Type:

Technical Notes

Industries:

Pharmaceutical/Biopharmaceutical

Techniques:

HPLC / UHPLC

Brands:

Yarra Phenex

PDF Link:

Click here