Organic Solvent in Size Exclusion Chromatography of an Antibody Drug Conjugate Surrogate

Abstract:

In this application note, we demonstrate the effect of organic solvent on SEC analysis of an ADC “mimic.” This sample is a monoclonal antibody that has been conjugated to a dansyl group and functions as a surrogate for the typically cytotoxic agent commonly used for most ADC modalities.

Document Type:

Technical Notes

Industries:

Pharmaceutical/Biopharmaceutical

Techniques:

HPLC / UHPLC

Brands:

bioZen

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