Polysorbate 80 (Tween 80) HPLC-UV Analysis on a Yarra 1.8 μm SEC-X150 Aqueous GFC/SEC Column

Abstract:

Polysorbate 80, also known as Tween 80, is very popular in the pharmaceutical, food, and cosmetic industries as an excipient, or inactive ingredient, in products such as tablets, vaccines, intravenous preparations, lotions, and soaps. The primary role of this pharmaceutical excipient is a solubilizing agent acting as a surfactant to assist with the solubility of all other pharmaceutical ingredients and also dissolution of the tablet. In the food and cosmetic industries, Tween 80 is used as an emulsifier for dissolving oils, as well as a surfactant. In this application, Tween 80 is analyzed by HPLC-UV using a Yarra 1.8 μm SEC-X150 150 x 4.6 mm aqueous size exclusion (SEC), or gel filtration chromatography (GFC), column in under 12 minutes.

Document Type:

Technical Notes

Industries:

Pharmaceutical/Biopharmaceutical Personal Care/Consumer Products Specialty Chemical/Industrial Food & Beverage

Techniques:

HPLC / UHPLC

Brands:

Yarra

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