Purification of Optically Active Pharmaceutical Compounds using Axial Compressed Columns (TN-1056)

Abstract:

A major improvement in preparative chiral column performance has been achieved by adapting axial compression to manufacture Lux chiral preparative columns. This paper demonstrates the advantages of combining the new Lux media and Axia packing technology to produce high performance stable preparative chiral columns. This new process produces preparative columns packed with 5 μm media with the same efficiency (plates per meter) in prep columns as found in analytical columns and peak symmetry independent of column length and internal diameter

Document Type:

Technical Notes

Industries:

Pharmaceutical/Biopharmaceutical

Techniques:

Preparative SFC

Brands:

Axia Lux

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