Separation of Synthetic Benzodiazepines by SPE and LC-MS/MS

Abstract:

Benzodiazepines are some of the highest prescribed drugs in the US, with significant abuse potential. "Synthetic" benzodiazepines (which are not FDA approved) are increasingly found in the population as well. It is important to be able to track these substances as they arise so they can be monitored and detected. They show cross reactivity with other benzodiazepines in immunoassays, so developing effective LC-MS/MS techniques are important for proper identification and quantification.

Document Type:

Technical Notes

Industries:

Pharmaceutical/Biopharmaceutical Clinical

Techniques:

Sample Prep

Brands:

Kinetex Strata-X

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