Successful Separation of Cannabidiol Enantiomers by LC-UV Analysis using Lux Amylose Chiral Columns

Abstract:

Cannabidiol (CBD) is a phytocannabinoid found in Cannabis, and a major focus of both pharmaceutical research and consumer products. CBD formed from within the plant is created by an enzyme-mediated process which exclusively forms the levorotatory isomer, (-)-cannabidiol, as has been confirmed by optical rotation and NMR analysis of plant extracted and purified material. The first synthetic approach to cannabinoids was based on the use of commercially available, chiral starting materials. This approach is still used in many pharmaceutical synthetic processes this day. For the development of plant-based cannabinoid products, having the ability to verify enantiomeric purity would be an excellent opportunity for quality verification of their products.

Document Type:

Technical Notes

Industries:

Cannabis Pharmaceutical/Biopharmaceutical

Techniques:

HPLC / UHPLC

Brands:

Lux

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