The Effectiveness of Polar Stationary Phase Modification on Peak Shape for Basic Compounds Under General Reversed Phase Conditions - A Comparison of Four Alkyl C18 Phases_

Abstract:

Described in this application note are the details for an investigation of basic compound peak shape across four different alkyl C18 stationary phases that are all based upon the same core-shell HPLC/UHPLC particle morphology. The goal of this application was to investigate the effect of a stationary phase modification and specifically the effect of a positive surface charge modification on peak shape for basic compounds under general reversed phase conditions.

Document Type:

Technical Notes

Industries:

Pharmaceutical/Biopharmaceutical Cannabis Environmental Food & Beverage Forensics/Toxicology Fuels Personal Care/Consumer Products Agriculture Specialty Chemical/Industrial Life Science

Techniques:

HPLC / UHPLC

Brands:

Kinetex

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