High pH Chiral Separations of Amphetamine and Substituted Amphetamines with the Polysaccharide-based Lux® 3 μm AMP Column (TN-1214:)

Abstract:

In this technical note, we demonstrate that the use of higher pH (>9) under reversed phase mode can dramatically improve the chiral separation of various amphetamine derivatives such as Methamphetamine, Ephedrine, Amphetamine, and 3,4-Methylenedioxymethamphetamine.

Document Type:

Technical Notes

Industries:

Pharmaceutical/Biopharmaceutical Forensics/Toxicology

Techniques:

HPLC / UHPLC

Brands:

Lux

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