Tricyclic Antidepressants from Plasma by LC-MS/MS (TN-0056)

Abstract:

Using an automated SPE method that requires no condition or equilibration steps, time and solvent are saved during the analysis of 9 tricyclic antidepressant (TCA) compounds from human plasma. The rapid automated procedure proved to be reproducible and provided absolute recoveries >75% for all TCA compounds studied. Coupled to a rapid LC/MS/MS method using a Kinetex core-shell HPLC/UHPLC column, this method can instantly provide time and solvent savings to high throughput laboratories.

Document Type:

Technical Notes

Industries:

Clinical Forensics/Toxicology

Techniques:

Sample Prep HPLC / UHPLC

Brands:

Kinetex Strata-X

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