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Introducing Kinetex F5
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Kinetex F5
Core-shell LC Columns

  • • Greater reproducibility than other PFPs
  • • 5 Glorious Interaction Mechanisms
  • • 5 Valuable Separation Modes
Available Particle Sizes
Pentafluorophenyl
NEW!

5

5

Versatile F5 Interaction Mechanisms

With the astonishing combination of core-shell performance and 5 interaction mechanisms, Kinetex F5 columns will effortlessly drive your orothoganol HPLC/UHPLC development!

A
Hydrophobic
Carbon skeleton of linker and ring encourage neutrality/hydrophobic retention
B
Aromatic
In non-acetonitrile mobile phases, π- π electrons of the carbon ring interact with analyte π- π electrons and result in positive retention increase
C
Electrostatic
High electronegativity of the fluorine groups create dipole moments, aiding in polar compound retention. Induced dipole moments can also aid neutral compound retention
D
Steric/Planar
Shape selectivity allows for isomeric separations that are otherwise impossible on traditional alkyl phases
E
Hydrogen Bonding
Extremely effective retention mechanism caused as polar functional groups of analyte interact with the electron greedy fluorine

5

5

Valuable LC Separation Modes

Combine core-shell performance, multiple retention mechanisms and the Kinetex F5 column's ability to be run in a variety of separation modes and you now have an impeccable method development tool at your disposal.

1. Reversed Phase

Separate compound mixtures with moderately polar mobile phase and the polar/nonpolar selectivity of Kinetex F5

2. 2D-LC

Utilize the Kinetex F5 orthogonal selectivity in series with a C18 for identification work

3. HILIC

Polar selectivity of Kinetex F5 is used in combination with high organic mobile phase to concentrate on polar compound retention

4. SFC

Supercritical carbon dioxide (CO2) and modifier (usually alcohols) mobile phase with Kinetex F5 for achiral separation

5. 100% Aqueous

Focus on polar compound retention with completely polar mobile phase

F

5

Unmatched Consistency and Accuracy

Conventional fully porous and core-shell PFP/F5 columns fail to reach the level of repeatability that you deserve. Inconsistencies in their base silica have led to data inaccuracies that waste your time and money. Kinetex F5 columns were specifically designed to avoid these past problems and provide you with the highest degree of reproducibility.